Publications

Publications

AIMS-2-TRIALS scientists contribute to publications from not only this research programme, but also to others. All of these publications are listed below. Those that are specific to AIMS-2-TRIALS and which have key findings will be covered in more detail on the News page.

Janssen, J., Díaz-Caneja, C. M., Alloza, C., Schippers, A., de Hoyos, L., Santonja, J., Gordliza, P. M., Bumier, E. E., Neeltje, E. M., van Haren, N. E., Chan, W., Arango, C., Kahn, H. E., Hulshoff, P. and Schnack, G. (2020). Dissimilarity in sulcal width patterns in the cortex can be used to identify patients with schizophrenia with extreme deficits in cognitive performance. Preprint in bioRxiv.

Eyre, M., Fitzgibbon, S. P., Ciarrusta, J., Cordero-Grande, L., Price, A. N., Poppe, T.,  Schuh, A., Hughes, E., O’Keeffe, C., Brandon, J., Cromb, D., Vecchiato, K., Andersson, J., Duff, E. P., Counsell, S. J., Smith, S. M., Rueckert, D., Hajnal, J. V., Arichi, T., O’Muircheartaigh, J., Batalle, D and Edwards, D. (2020). The Developing Human Connectome Project: typical and disrupted functional connectivity across the perinatal period. Preprint in bioRxiv.

Martins, D., Mazibuko, N., Zelaya, F., Vasilakopolou, S., Loveridge, J., Oates, A., Maltezos, S., Mehta, M., Wastling, S., Howard, M., McAlonan, G., Murphy, D., Williams, S., Fotopoulou, A., Schuschnig, U. and Paloyelis, Y. (2020). Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans. Nature Communications. (Accepted).

Ching, C. R. K., Gutman, B. A., Sun, D., Reina, J. V., Ragothaman, A., Isaev, D., Zavaliangos-Petropulu, A., Lin, A., Jonas, R. K., Kushan, L., Pacheco-Hansen, L., Vajdi, A., Forsyth, J. K., Jalbrzikowski, M., Bakker, G., van Amelsvoort, T., Antshel, K. M., Fremont, W., Kates, W. R., Campbell, L. E., McCabe, K. L., Craig, M. C., Daly, E., Gudbrandsen, M., Murphy, C. M., Murphy, D. G., Murphy, K. C., Fiksinski, A., Koops, S., Vorstman, J., Crowley, T. B., Emanuel, B. S., Gur, R. E., McDonald-McGinn., D. M., Roalf, D. R., Ruparel, K., Schmitt, J. E., Zackai, E. H., Durdle, C. A., Goodrich-Hunsaker, N. J., Simon, T. J., Bassett, A. S., Butcher, N. J., Chow, E. W. C., Vila-Rodriguez, F., Cunningham, A., Doherty, J., Linden, D. E., Moss, H., Owen, M. J., van den Bree, M., Crossley, N. A., Repetto, G. M., Thompson, P. M. and Bearden, C. E. (2020). Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence with Idiopathic Neuropsychiatric Illness. American Journal of Psychiatry.

Cursano, S., Battaglia, C.R., Urrutia-Ruiz, C., Grabrucker, S., Schön, M., Bockmann, J., Braumüller, S., Radermacher, P., Roselli, F., Huber-Lang, M. and Boeckers, T.M. (2020). A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndromeMolecular Psychiatry, 1-17.

Lord, C., Traolach, B. S., Charman, T., Cusack, J., Dumas, G., Frazier, T., Jones, E. J. H., Pickles, A., Jones, R. M., State, M. W., Lounds Taylor, J., Veenstra-VenderWeele, J. (2020). Autism Spectrum Disorder. Nature Reviews Disease Primers, 6(5).

Rocktäschel, P., Sen, A., and Cader, M. Z. (2019). High glucose concentrations mask cellular phenotypes in a stem cell model of tuberous sclerosis complexEpilepsy & Behavior, 106581.

Van Kessel, R., Walsh, S., Ruigrok, A.N., Holt, R., Yliherva, A., Kärnä, E., Moilanen, I., Hjörne, E., Johansson, S.T., Schendel, D. and Pedersen, L., Jørgensen, M., Brayne, C., Baron-Cohen, S., and Roman Urrestarazu, A. (2019). Autism and the right to education in the EU: policy mapping and scoping review of Nordic countries Denmark, Finland, and Sweden. Molecular Autism, 10(1), 44.

Van Kessel, R., Roman-Urrestarazu, A., Ruigrok, A., Holt, R., Commers, M., Hoekstra, R.A., Czabanowska, K., Brayne, C. and Baron-Cohen, S. (2019). Autism and family involvement in the right to education in the EU: policy mapping in the Netherlands, Belgium and Germany. Molecular Autism, 10(1), 1-18.

Pan, P. Y., Tammimies, K. and Bölte, S. (2019). The Association Between Somatic Health, Autism Spectrum Disorder, and Autistic Traits. Behavior Genetics, 1-14.

Rodriguez-Toscano, E., López, G., Mayoral, M., Lewis, S., Lees, J., Drake, R., Arango, C. and Rapado-Castro (2019). A longitudinal comparison of two neurocognitive test batteries in patients with schizophrenia and healthy volunteers: Time effects on neuropsychological performance and their relation to functional outcome. Schizophrenia Research.

Jesse, S., Müller, H. P., Schoen, M., Asoglu, H., Bockmann, J., Huppertz, H. J., Ludolph, A.C., Boeckers, T.M. and Kassubek, J. (2019). Severe white matter damage in SHANK3 deficiency: a human and translational study. Annals of Clinical and Translational Neurology.

Rapado-Castro, M., Moreno, C., Ruíz-Sancho, A., Camino, F., Arango, C., and Mayoral, M. (2019). Role of Executive Function in Response to a Problem Solving Based Psychoeducational Intervention in Adolescents with Psychosis: The PIENSA Trial Revisited. Journal of Clinical Medicine8(12), 2108.

Jones, E. J. H., Mason, L., Begum Ali, J., van den Boomen, C., Braukmann, R., Cauvet, E., Demurie, E., Hessels, R. S., Ward, E. K., Hunnius, S., Bolte, S., Tomalski, P., Kemner, C., Warreyn, P., Roeyers, H., Buitelaar, J., Falck-Ytter, T., Charman, T. and Johnson, M. H. (2019). Eurosibs: Towards robust measurement of infant neurocognitive predictors of autism across Europe.  Infant Behavior and Development57, 101316.

Wichers, R. H., Findon, J. L., Jelsma, A., Giampietro, V., Stoencheva, V., Robertson, D. M., Murphy, C. M., McAlonan, G., Ecker, C., Rubia, K., Murphy, D. G. M. and Daly, E. (2019). Modulation of brain activation during executive functioning in autism with citalopram. Translational psychiatry9(1), 1-11.

Postema, M. C., Van Rooij, D., Anagnostou, E., Arango, C., Auzias, G., Behrmann, M., Busatto Folho, G., Caleroni, S., Calvo, R., Daly, E. and Deruelle, C. (2019). Altered structural brain asymmetry in autism spectrum disorder in a study of 54 datasets. Nature Communications10(1), 1-12.

Nyström, P., Thorup, E., Bölte, S. and Falck-Ytter, T. (2019). Joint attention in infancy and the emergence of autism. Biological Psychiatry, 86(8), 631-638.

Wolfers, T., Floris, D. L., Dinga, R., van Rooij, D., Isakoglou, C., Kia, S. M., Zabihi, M., Llera, A., Chowanayaka, R., Kumar, V. J., Laidi, C., Batalle, D., Dimitrova, R., Charman, T., Loth, E., Lai, M. C., Jones, E., Baumeister, S., Moessnang, C., Banaschewski, T., Ecker, C., Dumas, G., O’Muircheartaigh, J., Murphy, D., Buitelaar, J. K., Marquand, A. F. and Beckmann, C. F. (2019). From pattern classification to stratification: towards conceptualizing the heterogeneity of Autism Spectrum Disorder. Neuroscience & Biobehavioral Reviews, 104, 240-254.

Austin, C., Curtin, P., Curtin, A., Gennings, C., Arora, M., Tammimies, K., Isaksson, J., Willfors, C. and Bölte, S. (2019). Dynamical properties of elemental metabolism distinguish attention deficit hyperactivity disorder from autism spectrum disorder. Translational Psychiatry 9(1), 1-9.

Bast, N., Banaschewski, T., Dziobek, I., Brandeis, D., Poustka, L. and Freitag, C. M. (2019). Pupil dilation progression modulates aberrant social cognition in Autism Spectrum Disorder. Autism Research, 12(11), 1680-1692.

Griffiths, S., Allison, C., Kenny, R., Holt, R., Smith, P., & Baron‐Cohen, S. (2019). The Vulnerability Experiences Quotient (VEQ): A study of vulnerability, mental health and life satisfaction in autistic adultsAutism Research12(10), 1516-1528.

Pretzsch, C.M., Voineschu, B., Mendez, M. A., Wichers, R., Airam, L., Ivin, G., Heasman, M., Williams, S., Murphy, D., Daly, E. and McAlonan, G. M. (2019). The effect of cannabidiol (CBD) on low-frequency activity and functional connectivity in the brain of adults with and without autism spectrum disorder (ASD). Journal of Psychopharmacology 44(8):1398-1405.

Sauer, A. K., Bockmann, J., Steinestel, K., Boeckers, T. M., & Grabrucker, A. M. (2019). Altered intestinal morphology and microbiota composition in the autism spectrum disorders associated SHANK3 mouse modelInternational journal of molecular sciences20(9), 2134.

Bedford, S. A., Park, M. T. M., Devenyi, G. A., Tullo, S., Germann, J., Patel, R., Anagnostou, E., Baron-Cohen, S., Bullmore, E. T., Chura, L. R., Craig, M. C., Ecker, C., Floris, D. L., Holt, R., Lenroot, R., Lerch, J. P., Lombardo, M. V., Murphy, D. G. M., Raznahan, A., Ruigrok, A. N. V., Smith, E., Spencer, M. D., Suckling, J., Taylor, M. J., Thurm, A., MRC AIMS Consortium., Lai, M-C., Chakravarty, M. M. (2019) Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder. Molecular psychiatry, 1-15.

Loth, E. & Evans, D.W. (2019). Converting tests of fundamental social, cognitive, and affective processes into clinically useful bio‐behavioral markers for neurodevelopmental conditions. WIREs Cognitive Science Volume 10, Issue 5.

Loth, E. and Evans, D.W. (2019). Converting tests of fundamental social, cognitive, and affective processes into clinically useful bio-behavioural markers for neurodevelopmental conditions. Wiley Interdisciplinary Reviews: Cognitive Science, 10(5), e1499.

Oldehinkel, M., Mennes, M., Marquand, A., Charman, T., Tillmann, J., Ecker, C., Dell’Acqua, F., Brandeis, D., Banaschewski, T., Baumeister, S. and Moessnang, C., Baron-Cohen, S., Holt, R., Bölte, S., Durston, S., Kundu, P., Lombardo, M., Spooren, W., Loth, E., Murphy, D., Beckmann, C., Buitelaar, J. and the EU-AIMS LEAP group. (2019). Altered connectivity between cerebellum, visual, and sensory-motor networks in autism spectrum disorder: results from the EU-AIMS Longitudinal European Autism Project.  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging4(3), 260-270.

Holiga, Š., Hipp, J.F., Chatham, C.H., Garces, P., Spooren, W., D’Ardhuy, X.L., Bertolino, A., Bouquet, C., Buitelaar, J.K., Bours, C. and Rausch, A., Oldehinkel, M., Bouvard, M., Amestoy, A., Caralp, M., Gueguen, S., Moal, M. L-L., Houenou, J., Beckmann, C. F., Loth, E., Murphy, D., Charman, T., Tillmann, J., Laidi, C., Delorme, R., Beggiato, A., Gaman, A., Scheid, I., Leboyer, M., D’Albis, M-A., Sevigny, J., Czech, C., Bolognani, F., Honey, G. D. and Dukart, J. (2019). Patients with autism spectrum disorders display reproducible functional connectivity alterations. Science Translational Medicine, 11(481), eaat9223.

Pote, I., Wang, S., Sethna, V., Blasi, A., Daly, E., Kuklisova-Murgasova, M., Lloyd-Fox, S., Mercure, E., Busuulwa, P., Stoencheva, V., Charman, T., Williams, S., Johnson, M., Murphy, D., McAlonan, G., and the BASIS team. (2019). Familial risk of autism alters subcortical and cerebellar brain anatomy in infants and predicts the emergence of repetitive behaviours in early childhood. Autism Research, 12(4): 614-627.

Tillmann, J., San José Cáceres, A., Chatham, C., Crawley, D., Holt, R., Oakley, B., Banaschewski, T., Baron-Cohen, S., Bölte, S., Buitelaar, J., Durston, S., Ham, L., Loth, E., Simonoff, E., Spooren, W., Murphy, D. and Charman, T. (2019). Investigating the factors underlying adaptive functioning in autism in the EU‐AIMS Longitudinal European Autism Project. Autism Research12(4), 645-657.

Pretzsch, C. M., Freyberg, J., Voinescu, B., Lythgoe, D., Horder, J., Mendez, M. A., Wichers, R., Airam, L., Ivin, G., Heasman, M., Edden, R., Williams, S., Murphy, D., Daly, E. and McAlonan. (2019). Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder. Neuropsychopharmacology, 44(8): 1398-1405.

Diaz-Caena, C. M., Schnack, H., Martínez, K., Santonja, J., Alemán‐Gomez, Y., Pina-Camacho, L., Moreno, C., Fraguas, D., Arango, C., Parellada, M. and Janssen, J. (2018). Neuroanatomical deficits shared by youth with autism spectrum disorders and psychotic disorders. Human Brain Mapping40(5), 1643-1653.

Greenberg, D. M., Warrier, V., Allison, C. and Baron-Cohen, S. (2018). Testing the empathizing-systemizing theory of sex differences and the extreme male brain theory of autism in half a million people. Proceedings of the National Academy of Sciences115(48), 12152-12157.

Horder, J., Andersson, M., Mendez, M. A., Singh, N., Tangen, A., Lundberg, J., Gee, A., Halldin, C., Veronese, M., Bölte , S., Farde, L., Sementa, T., Cash, D., Higgins, K., Spain, D., Turkheimer, F., Mick, I., Selvaraj, S., Nutt, D., Lingford-Hughes, A., Howes, O., Murphy, D. and Borg, J. (2018). GABA-A receptor availability is not altered in adults with autism spectrum disorder or in mouse models. Science Translational Medicine, 10(461): eaam8434.