Publications
Publications

AIMS-2-TRIALS scientists contribute to publications from not only this research programme, but also to others. All of the publications that recognise a financial contribution from AIMS-2-TRIALS are listed below. The publications that are specific to AIMS-2-TRIALS and which have key findings will be covered in more detail on the News pageBecause the process from research manuscript submission to publication may take a long time, authors can post their manuscripts as “preprints” on websites such as bioRxiv to immediately share their findings and allow for discussion and peer feedback during the publication process. All publications listed below are published in “peer reviewed” journals, the publications listed in the box on the right are “preprints”. Visit Spectrum News’s blog post for more information about preprint publications. 

2020

Moessnang, C., Baumeister, S., Tillman, J., Goyard, D., Charman, T., Ambrosino, S., Baron-Cohen, S., Beckmann, C., Bölte, S., Bours, C., Crawley., … and the EU-AIMS LEAP group. (2020). Social brain activation during mentalizing in a large autism cohort: the Longitudinal European Autism Project. Molecular Autism. 11(17). Published 22nd February, 2020.

Ching, C. R. K., Gutman, B. A., Sun, D., Reina, J. V., Ragothaman, A., Isaev, D., Zavaliangos-Petropulu, A., Lin, A., Jonas, R. K., Kushan, L., … and Bearden, C. E. (2020). Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence with Idiopathic Neuropsychiatric Illness. American Journal of Psychiatry. Published 12th February, 2020.

Martins, D., Mazibuko, N., Zelaya, F., Vasilakopolou, S., Loveridge, J., Oates, A., Maltezos, S., Mehta, M., Wastling, S., Howard, M., … and Paloyelis, Y. (2020). Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans. Nature Communications. (Accepted 29th January, 2020).

Cursano, S., Battaglia, C.R., Urrutia-Ruiz, C., Grabrucker, S., Schön, M., Bockmann, J., Braumüller, S., Radermacher, P., Roselli, F., Huber-Lang, M. and Boeckers, T.M. (2020). A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndromeMolecular Psychiatry, 1-17. Published 20th January, 2020.

Lord, C., Traolach, B. S., Charman, T., Cusack, J., Dumas, G., Frazier, T., Jones, E. J. H., Pickles, A., Jones, R. M., State, M. W., … and Veenstra-VanderWeele, J. (2020). Autism Spectrum Disorder. Nature Reviews Disease Primers, 6(5). Published 16th January, 2020.

2019

Rocktäschel, P., Sen, A., and Cader, M. Z. (2019). High glucose concentrations mask cellular phenotypes in a stem cell model of tuberous sclerosis complexEpilepsy & Behavior, 106581. Published December, 2019.

Van Kessel, R., Walsh, S., Ruigrok, A.N., Holt, R., Yliherva, A., Kärnä, E., Moilanen, I., Hjörne, E., Johansson, S.T., Schendel, D., … and Roman-Urrestarazu, A. (2019). Autism and the right to education in the EU: policy mapping and scoping review of Nordic countries Denmark, Finland, and Sweden. Molecular Autism, 10(1), 44. Published 11th December, 2019. 

Van Kessel, R., Roman-Urrestarazu, A., Ruigrok, A., Holt, R., Commers, M., Hoekstra, R.A., Czabanowska, K., Brayne, C. and Baron-Cohen, S. (2019). Autism and family involvement in the right to education in the EU: policy mapping in the Netherlands, Belgium and Germany. Molecular Autism, 10(1), 1-18. Published 9th December, 2019.

Pan, P. Y., Tammimies, K. and Bölte, S. (2019). The Association Between Somatic Health, Autism Spectrum Disorder, and Autistic Traits. Behavior Genetics, 1-14. Published 6th December, 2019.

Rodriguez-Toscano, E., López, G., Mayoral, M., Lewis, S., Lees, J., Drake, R., Arango, C. and Rapado-Castro (2019). A longitudinal comparison of two neurocognitive test batteries in patients with schizophrenia and healthy volunteers: Time effects on neuropsychological performance and their relation to functional outcome. Schizophrenia Research. Published 6th December, 2019. 

Jesse, S., Müller, H. P., Schoen, M., Asoglu, H., Bockmann, J., Huppertz, H. J., Ludolph, A.C., Boeckers, T.M. and Kassubek, J. (2019). Severe white matter damage in SHANK3 deficiency: a human and translational study. Annals of Clinical and Translational Neurology. Published 2nd December, 2019.

Rapado-Castro, M., Moreno, C., Ruíz-Sancho, A., Camino, F., Arango, C., and Mayoral, M. (2019). Role of Executive Function in Response to a Problem Solving Based Psychoeducational Intervention in Adolescents with Psychosis: The PIENSA Trial Revisited. Journal of Clinical Medicine8(12), 2108. Published 2nd December, 2019.

Jones, E. J. H., Mason, L., Begum Ali, J., van den Boomen, C., Braukmann, R., Cauvet, E., Demurie, E., Hessels, R. S., Ward, E. K., Hunnius, S., … and the Eurosibs team. (2019). Eurosibs: Towards robust measurement of infant neurocognitive predictors of autism across Europe. Infant Behavior and Development57, 101316. Published November, 2019.

Wichers, R. H., Findon, J. L., Jelsma, A., Giampietro, V., Stoencheva, V., Robertson, D. M., Murphy, C. M., McAlonan, G., Ecker, C., Rubia, K., … and Daly, E. (2019). Modulation of brain activation during executive functioning in autism with citalopram. Translational psychiatry9(1), 1-11. Published 11th November, 2019.

Postema, M. C., Van Rooij, D., Anagnostou, E., Arango, C., Auzias, G., Behrmann, M., Busatto Folho, G., Caleroni, S., Calvo, R., Daly, E. and Deruelle, C. (2019). Altered structural brain asymmetry in autism spectrum disorder in a study of 54 datasets. Nature Communications10(1), 1-12. Published 31st October, 2019. 

Nyström, P., Thorup, E., Bölte, S. and Falck-Ytter, T. (2019). Joint attention in infancy and the emergence of autism. Biological Psychiatry, 86(8), 631-638. Published 15th October, 2019. 

Wolfers, T., Floris, D. L., Dinga, R., van Rooij, D., Isakoglou, C., Kia, S. M., Zabihi, M., Llera, A., Chowanayaka, R., Kumar, V. J., … and Beckmann, C. (2019). From pattern classification to stratification: towards conceptualizing the heterogeneity of Autism Spectrum Disorder. Neuroscience & Biobehavioral Reviews, 104, 240-254. Published September, 2019.

Austin, C., Curtin, P., Curtin, A., Gennings, C., Arora, M., Tammimies, K., Isaksson, J., Willfors, C. and Bölte, S. (2019). Dynamical properties of elemental metabolism distinguish attention deficit hyperactivity disorder from autism spectrum disorder. Translational Psychiatry 9(1), 1-9. Published 25th September, 2019. 

Bast, N., Banaschewski, T., Dziobek, I., Brandeis, D., Poustka, L. and Freitag, C. M. (2019). Pupil dilation progression modulates aberrant social cognition in Autism Spectrum Disorder. Autism Research, 12(11), 1680-1692. Published 25th July, 2019.

Griffiths, S., Allison, C., Kenny, R., Holt, R., Smith, P., & Baron‐Cohen, S. (2019). The Vulnerability Experiences Quotient (VEQ): A study of vulnerability, mental health and life satisfaction in autistic adultsAutism Research12(10), 1516-1528. Published 5th July, 2019. 

Pretzsch, C.M., Voineschu, B., Mendez, M. A., Wichers, R., Airam, L., Ivin, G., Heasman, M., Williams, S., Murphy, D., Daly, E. and McAlonan, G. M. (2019). The effect of cannabidiol (CBD) on low-frequency activity and functional connectivity in the brain of adults with and without autism spectrum disorder (ASD). Journal of Psychopharmacology 44(8):1398-1405. Published 25th June, 2019. 

Sauer, A. K., Bockmann, J., Steinestel, K., Boeckers, T. M., & Grabrucker, A. M. (2019). Altered intestinal morphology and microbiota composition in the autism spectrum disorders associated SHANK3 mouse modelInternational journal of molecular sciences20(9), 2134. Published 30th April, 2019. 

Bedford, S. A., Park, M. T. M., Devenyi, G. A., Tullo, S., Germann, J., Patel, R., Anagnostou, E., Baron-Cohen, S., Bullmore, E. T., Chura, L. R., … and Chakravarty, M. (2019) Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder. Molecular psychiatry, 1-15. Published 26th April, 2019. 

Loth, E. and Evans, D.W. (2019). Converting tests of fundamental social, cognitive, and affective processes into clinically useful bio-behavioural markers for neurodevelopmental conditions. Wiley Interdisciplinary Reviews: Cognitive Science, 10(5), e1499. Published 3rd April, 2019.

Oldehinkel, M., Mennes, M., Marquand, A., Charman, T., Tillmann, J., Ecker, C., Dell’Acqua, F., Brandeis, D., Banaschewski, T., Baumeister, S., … and Buitelaar, J. (2019). Altered connectivity between cerebellum, visual, and sensory-motor networks in autism spectrum disorder: results from the EU-AIMS Longitudinal European Autism Project. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging4(3), 260-270. Published March, 2019.

Holiga, Š., Hipp, J.F., Chatham, C.H., Garces, P., Spooren, W., D’Ardhuy, X.L., Bertolino, A., Bouquet, C., Buitelaar, J.K., Bours, C., … and Dukart, J. (2019). Patients with autism spectrum disorders display reproducible functional connectivity alterations. Science Translational Medicine, 11(481), eaat9223. Published 27th February, 2019. 

Pote, I., Wang, S., Sethna, V., Blasi, A., Daly, E., Kuklisova-Murgasova, M., Lloyd-Fox, S., Mercure, E., Busuulwa, P., Stoencheva, V., … and the BASIS team. (2019). Familial risk of autism alters subcortical and cerebellar brain anatomy in infants and predicts the emergence of repetitive behaviours in early childhood. Autism Research, 12(4): 614-627. Published 22nd February, 2019. 

Tillmann, J., San José Cáceres, A., Chatham, C., Crawley, D., Holt, R., Oakley, B., Banaschewski, T., Baron-Cohen, S., Bölte, S., Buitelaar, J., … and the EU-AIMS LEAP group. (2019). Investigating the factors underlying adaptive functioning in autism in the EU‐AIMS Longitudinal European Autism Project. Autism Research12(4), 645-657. Published 11th February, 2019. 

Pretzsch, C. M., Freyberg, J., Voinescu, B., Lythgoe, D., Horder, J., Mendez, M. A., Wichers, R., Airam, L., Ivin, G., Heasman, M., … and McAlonan, G. (2019). Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder. Neuropsychopharmacology, 44(8): 1398-1405. Published 6th February, 2019.

Preprint publications

Floris, D. L., Wolfers, T., Zabihi, M., Holz, N. E., Zwiers, M. P., Charman, T., Tillmann, J., Ecker, C., Dell’Acqua, F., Banaschewski, T and Buitelaar, J. K. (2020). Atypical brain asymmetry in autism-a candidate for clinically meaningful stratification. Preprint in bioRxiv.

Bethlehem, R. A. I., Seidlitz, J., Romero-Garcia, R., Dumas, G., Lombardo, M. V. (2020). Normative age modelling of cortical thickness in autistic males. Preprint in bioRxiv.

Adhya, D., Swarup, V., Nagy, R., Dutan, L., Shum, C., Jozwik, K. M., Mendez, M. A., Horder, J., Nowosiad, P., Lee, I. and Skuse, D. (2020). Atypical neurogenesis in induced pluripotent stem cell (iPSC) from autistic individuals. Preprint in bioRxiv.

Peng, H., Gong, W., Beckmann, C. F., Vedaldi, A., Smith, S. M. (2020). Accurate brain age prediction with lightweight deep neural networks. Preprint in bioRxiv.

Chauvin, R. J., Buitelaar, J. K., Oldehinkel, M., Franke, B., Hartman, C. Heslenfeld, D. J., Hoekstra, P. J., Oosterlaan, J., Beckmann, C. F. and Mennes, M. (2020). An integrated analysis across separate task domains reveals a lack of common processing in the ADHD brain. Preprint in bioRxiv.

Bralten, J., Klemann, C. J. H. M., Mota, N. R., De Witte, W., Arango, C., Fabbri, C., Kas, M. J., van der Wee, N., Penninx, B. W. J. H., Serretti, A., … and Poelmans, G. (2020). Genetic underpinnings of sociability in the UK Biobank. Preprint in bioRxiv.

Procyshyn, T. L., Lombardo, M. V., Meng-Chuan, L., Auyeung, B., Crockford, S. K., Deakin, J., Soubramanian, S., Sule, A., Baron-Cohen, S. and Bethlehem, R. A. I. (2020). Salivary sex hormone levels following oxytocin administration in autistic and typical women. Preprint in bioRxiv.

Trakoshis, S., Martínez-Cañada, P., Rocchi, F., Canella, C., You, W., Chakrabarti, B., Ruigrok, A. N. V., Bullmore, E. T., Suckling, J., Markicevic, M., … and Lombardo, M. (2020). Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women. Preprint in bioRxiv.

Eyre, M., Fitzgibbon, S. P., Ciarrusta, J., Cordero-Grande, L., Price, A. N., Poppe, T., Schuh, A., Hughes, E., O’Keeffe, C., Brandon, J., … and Edwards, D. A. (2020). The Developing Human Connectome Project: typical and disrupted perinatal functional connectivity. Preprint in bioRxiv.

Bralten, J., Widomska, J., De Witte, W., Yu, D., Mathews, C. A., Scharf, J. M., Buitelaar, J., Crosbie, J., Schachar, R., Arnold, P., Lemire, M., … and Poelmans, G. (2020). Shared genetic etiology between obsessive-compulsive disorder, obsessive-compulsive symptoms in the population, and insulin signaling. Preprint in bioRxiv.

Boedhoe, P. S. W., van Rooij, D., Hoogman, M., Twisk, J. W. R., Schmaal, L., Abe, Y., Alonso, P., Ameis, S. H., Anikin, A., Anticevic, A., … and van den Heuvel, O. A. (2020). Subcortical brain volume, regional cortical thickness and cortical surface area across attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and obsessive-compulsive disorder (OCD). Preprint in bioRxiv.

Massrali, A., Brunel, H., Hannon, E., Wong, C., iPSYCH-MINERvA Epigenetics Group, Baron-Cohen, S. and Warrier, V. (2020) Integrated genetic and methylomic analyses identify shared biology between autism and autistic traits. Preprint in bioRxiv.

Biton, A., Traut, N., Poline, J-B., Aribisala, B. S., Bastin, M. E., Bülow, R., Cox, S. R., Deary, I, J., Grabe, H. J., Hagenaars, S., … and Toro, R. (2020). Polygenic architecture of human neuroanatomical diversity. Preprint in bioRxiv.

Warrier, V., Toro, R., Won, H., Leblond, C. S., Cliquet, F., Delorme, R., De Witte, W., Bralten, J., Chakrabarti, B., Børglum, A. D., … and Baron-Cohen, S. (2020). Social and non-social autism symptom and trait domains are genetically dissociable. Preprint in bioRxiv.

Postema, M. C., van Rooij, D., Anagnostou, E., Arango, C., Auzias, G., Behrmann, M., Filho, G. B., Calderoni, S., Calvo, R., Daly, E., … and Francks, C. (2020). Altered structural brain asymmetry in autism spectrum disorder: large-scale analysis via the ENIGMA Consortium. Preprint in bioRxiv.

Satterstrom, K. F., Kosmicki, J. A., Wang, J., Breen, M. S., De Rubeis, S., An, J-Y., Peng, M., Collins, R., Grove, J., Klei, L., … and Buxbaum, J. D. (2020). Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism. Preprint in bioRxiv.

Janssen, J., Díaz-Caneja, C. M., Alloza, C., Schippers, A., de Hoyos, L., Santonja, J., Gordliza, P. M., Bumier, E. E., Neeltje, E. M., van Haren, N. E., … and Schnack, H. G. (2020). Dissimilarity in sulcal width patterns in the cortex can be used to identify patients with schizophrenia with extreme deficits in cognitive performance. Preprint in bioRxiv.

Eyre, M., Fitzgibbon, S. P., Ciarrusta, J., Cordero-Grande, L., Price, A. N., Poppe, T., Schuh, A., Hughes, E., O’Keeffe, C., Brandon, J., … and Edwards, D. A. (2020). The Developing Human Connectome Project: typical and disrupted functional connectivity across the perinatal period. Preprint in bioRxiv.

2018

Diaz-Caena, C. M., Schnack, H., Martínez, K., Santonja, J., Alemán‐Gomez, Y., Pina-Camacho, L., Moreno, C., Fraguas, D., Arango, C., Parellada, M. and Janssen, J. (2018). Neuroanatomical deficits shared by youth with autism spectrum disorders and psychotic disorders. Human Brain Mapping40(5), 1643-1653. Published 19th December, 2018.

Greenberg, D. M., Warrier, V., Allison, C. and Baron-Cohen, S. (2018). Testing the empathizing-systemizing theory of sex differences and the extreme male brain theory of autism in half a million people. Proceedings of the National Academy of Sciences115(48), 12152-12157. Published 12th November, 2018.

Horder, J., Andersson, M., Mendez, M. A., Singh, N., Tangen, A., Lundberg, J., Gee, A., Halldin, C., Veronese, M., Bölte , S., … and Borg, J.  (2018). GABA-A receptor availability is not altered in adults with autism spectrum disorder or in mouse models. Science Translational Medicine, 10(461): eaam8434. Published 3rd October, 2018.